What domain software is good?
 

I'm looking for software where I can enter a keyword and it will combine it with other words. Then, check to see if the domains are available. I need something that can be ran from the desktop. Anyone have any suggestions?

Drop Shark

check out
http://domain-suggestions.domaintools.com/

dfrop shart?

Any other suggestions?

here is a good tool.:

http://www.mozzle.com/products/domain-name-search-pro/

it can do what you need + lots more...