Hangover free Alcohol Now Possible - YAY
 

Synthehol is a science-fictional substitute for alcohol that appears on the Star Trek:The Next Generation television series. It allows drinkers to experience all of the enjoyable, intoxicating effects of alcohol without unpleasant side-effects like hangovers.
Professor David Nutt, a psychopharmacologist at the University of Bristol in the UK, believes that there is no scientific reason why it cannot be created now.

Alcohol works in the brain mainly by latching onto signalling molecules called GABA-A receptors. There are dozens of subtypes of these; not all of them are associated with specific effects of alcohol. For example, memory loss may occur in conjuction with drinking because alcohol binds to alpha-5, a GABA-A receptor subtype in the hippocampus.

Professor Nutt suggests that if molecules that bind poorly to the bad subtypes like alpha-5 could be developed, it would be possible to retain the pleasant effects of alcohol without the bad side-effects.

Some "partial agonists" of GABA-A receptors already exist; bretazenil and pagoclone were developed as anti-anxiety drugs. These drug molecules are instantly reversible by the flumazenil, used as an antidote to overdoses of tranquillisers.

Perhaps most interesting is the idea that problems like cirrhosis of the liver could be eliminated by altering the composition of alcoholic beverages. Nutt will publish this idea in the Journal of Psychopharmacology next month.

http://www.livescience.com/scienceof...synthehol.html

Sounds awesome. Time to get hammered

Screw that, I want viagra beer.

A buddy of mine works for a drug company. I guess they make the anxiety drugs noted in that article because when you take his little pills and drink, you feel great and no hangover at all...

Mmmmm - Professor Nutt

What happened to that RU21 stuff - anyone try it?

Yeah nothing better than watching the game with your buds and getting wood that lasts into game 2.

thats great ! where can i get some ?

:pimp
That's what i'm talking about.

i don't get hangovers anymore! is that a good thing or bad thing??

thanks
tony

Nothing is like a good hangover... Had one this morning in fact!

11 beers last night...tossed down 3 advils and a big glass of ice water before crashing.

Was good to go this morning - no trace of hangover whatsoever. :thumbsup

If it was possible it would already be done.

nice, or you could snort some white stuff (not coke) and it will get you drunk without a hangover ;)

damn that would be very damn cool

I'd drink it! :thumbsup

I've been suffering from the most insane hangovers every single time I've been drinking my whole life .. but the last two times I've eaten a tee-spoon of salt and been drinking 4-5 glasses of water before going to water .. and it's been reducing my hang overs dramaticly