Mouse with two mothers and no father marks a first for mammals
 

This is some freaky shit..

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"Mouse with two mothers and no father marks a first for mammals
By Roger Highfield, Science Editor
(Filed: 22/04/2004)


A mouse has been born that has two mothers, but no father. The animal, named Kaguya - which could prove as controversial as Dolly the cloned sheep - shows for the first time that a particular kind of "virgin birth" is possible in mammals - and thus people.



The method, perfected by a team at the Tokyo University of Agriculture, with colleagues in Japan and Korea, marks the second advance, after cloning, that appears to make males redundant.

"This is very exciting and impressive," said Prof Ian Wilmut, head of the team that cloned Dolly.

Although the birth is an amazing feat - so much so that science does not yet have an accepted name for the technique - Prof Wilmut and other scientists stressed that the practical implications were obscure, since the method was even more complex, inefficient and unsafe than cloning.

Sexless reproduction abounds in nature, but not in mammals. Although unfertilised mouse eggs can be jolted into dividing with chemicals or electric shocks, the resulting embryos do not reach term.

Today, in the journal Nature, Dr Tomohiro Kono and colleagues describe how they produced live female mice, the first being Kaguya, without any need for sperm and male chromosomes.

Parthenogenesis - reproduction without fertilisation - was thought impossible in mammals due to imprinting, a mechanism that turns genes on and off depending on whether they come from the mother or father. At least 40 genes necessary for development are thought to be regulated in this way.

Rather than combine egg and sperm, Dr Kono combined a female imprinted genetic code from an older egg with a "male-like" imprinted female genetic code. The latter was created from the genome of a young egg, free of maternal imprinting. To masculinise it, Dr Kono used genetic engineering to remove a gene (H19) so that there was no H19 activity - as is normally the case in the father's genetic code.

Dr Kono told The Telegraph that it may be difficult to do this experiment in other species but it "is a possibility" in some domestic animals. He would not be drawn on whether two women could have a baby this way.

"This is an incredible achievement," said Prof Azim Surani of the University of Cambridge. But he added that it was too complex to be used on people.

Dr Anne Ferguson-Smith of Cambridge University said: "This paper does not mean that males are obsolete - the requirement for paternal chromosomes for normal development is still with us."


The scary part is that they can only produce a female mouse.. watch out guys :winkwink:

wicked...

I agree with that !!! :ugone2far

Ivy

Oh good, glad to see that we're not tampering with nature TOO much.

my question is can they make one with four asses yet?

http://superpopo.chez.tiscali.fr/MEPHISTO.JPG

fuck that shit. men will never laid again. :( :1orglaugh

The next thing we'll hear is that this mouse gave birth to a cross-breed mouse-cat! Now that's something!

fuck - that and an electric vibrator and it's all over for men everywhere...........

female domination.. we shall rule the world..BAHAHAHAHAHAHA!


or kill each other..lol

Don't worry, just as we build it, we tend to destroy it even faster. What do you think war is all about?

Man has a tendency to keep inventing shit to improve life and in the process threatens to render himself obsolete. We are envious of the female creative power but we are much better at destruction, especially when threatened with extinction..

Hehehe!!

Who will pay the child support then?

(Just kidding -- totaly woman-bashing remark -- you might have to come over the river and through the woods to kick my ass for that one, C_U_Next_Tuesday) :Graucho

I was just thinking about you.. and I am dying to come back to the coast!

Are you going to the dormangels pajama party on May 15th?

ooooh, lesbian mice

Betty, Trixie - what do you guys (hehehe) think about content like this?

http://www.gofuckyourself.com/showth...hreadid=272955

curious how women view this.

I'll answer you over in that thread :glugglug

All I can say is on the one hand, I'm sure it really sells.....on the other, OMG why do girls do shit like that for cash??
:uhoh

Ivy

anything is possible. anything.

Your days are numbered guys

btw- "The children of men" written by P.D. James is an excellent fictional account of a time when men become infertile.

Not extreme enough for me. :Graucho

Seriously though, that stuff doesn't bother me too much and with a nice incest story line thrown into the bargain I can really get off on it. Errrr. Wait. What I meant to say is, there are tons of sites and movies with content like that -- it's kind of played out. They need to mix it up with some GUYS coughing and choking and gagging on my monstrous strap-on. That's it pretty boy, take my big floppy dong!

Evolution NEEDS males.

The reason being that males produce more gametes on a daily basis which increases the chance of mutation hence genetic diversity for any given genetic population pool.

EXACTLY what i was thinking.

Wouldn't it be more shocking if they got the father carry the sibling? :2 cents:

Don't worry, the ACLU is already filing a lawsuit on it.

:1orglaugh :1orglaugh :1orglaugh