>> FDA says NO to medical marijuana - GoFuckYourself.com

luv$ · 04-21-2006, 12:27 PM

WASHINGTON (AP) -- The Food and Drug Administration said Thursday that it does not support the use of marijuana for medical purposes.

The FDA said in a statement that it and other agencies with the Health and Human Services Department had "concluded that no sound scientific studies supported medical use of marijuana for treatment in the United States, and no animal or human data supported the safety or efficacy of marijuana for general medical use."

A number of states have passed legislation allowing marijuana use for medical purposes, but the FDA said, "These measures are inconsistent with efforts to ensure that medications undergo the rigorous scientific scrutiny of the FDA approval process and are proven safe and effective."

The statement contradicts a 1999 finding from the Institute of Medicine, part of the National Academy of Sciences, which reported that "marijuana's active components are potentially effective in treating pain, nausea, the anorexia of AIDS wasting and other symptoms, and should be tested rigorously in clinical trials."

Bruce Mirken, director of communications for the Marijuana Policy Project, said Thursday: "If anybody needed proof that the FDA has become totally politicized, this is it. This isn't a scientific statement; it's a political statement."

Mirken said "a rabid congressional opponent of medical marijuana," Rep. Mark Souder, R-Indiana, asked the FDA to make the statement.

Souder, chairman of the House Government Reform subcommittee on drug policy, has said the promotion of medical marijuana "is simply a red herring for the legalization of marijuana for recreational use. Studies have continually rejected the notion that marijuana is suitable for medical use because it adversely impacts concentration and memory, the lungs, motor coordination and the immune system."

The FDA statement noted "there is currently sound evidence that smoked marijuana is harmful." It also said, "There are alternative FDA-approved medications in existence for treatment of many of the proposed uses of smoked marijuana."

Mirken responded, "There is abundant evidence that marijuana can help cancer patients, multiple sclerosis patients and AIDS patients. There is no scientific doubt that marijuana relieves nausea, vomiting, certain kinds of pain and other symptoms that don't respond well to conventional drugs, and does it more safely than other drugs.

"For the FDA to ignore all that evidence is embarrassing," Mirken said. "They should be red-faced."

http://www.cnn.com/2006/HEALTH/04/21....ap/index.html

Rui · 04-21-2006, 12:29 PM

of course...how could they approve something the big pharma companys cant make money with and everybody can grow themselfs...tskk tskk

After Shock Media · 04-21-2006, 12:53 PM

It is very typical of them though and I would not expect less.

Best part is that the US Government will not allow independant medical labs to have marijuana to do research on the begin with.

Then to add in a wonderful twist to the equation. The FDA has approved Marinol a synthetic ingested marijuana. Marinol though has this tricky issue of it being in pill form and thus does nothing for those suffering from nausea since you are prone to throwing it up. Also unlike its natural form a patient can OD on Marinol. So if there are no medical uses for it why then Marinol?

As for medical studies.

Unintentional weight loss in HIV/AIDS patients is still common, even in this era of highly active antiretroviral therapy (HAART). This unexpected finding has been documented in a cohort of patients from the Tufts University Nutrition for Healthy Living (NFHL) study?a large longitudinal, observational study initiated in February 1995 and continuing through 2005.

Patients: Wanke and colleagues1 evaluated 633 HIV/AIDS patients enrolled in the NFHL study. Most of these patients (67%) were on HAART. Participants received nutritional and health assessments at baseline and every 6 months

Endpoints: Researchers determined the percentage of patients who met at least one definition of significant weight loss found in the literature

As shown in the chart, significant weight loss was common in this population despite the use of HAART.

MULTIPLE CLINICAL CHALLENGES IN CANCER
Chemotherapy-induced nausea and vomiting (CINV) is still a common problem.
Despite treatment with a 5-HT3 antagonist, CINV persists in 40% to 60% of patients on highly emetogenic therapy1

Up to 80% of patients on cisplatin experience delayed CINV2

A recent survey demonstrates that CINV is common even with treatments.3

Participants: The multicenter survey included 298 chemotherapy-naïve patients with cancer and their health care professionals (24 physicians and nurses)

Nearly all (97%) of the patients received a 5-HT3 antagonist, 78% received a corticosteroid, and all received either highly (22%) or moderately (78%) emetogenic agents.

Endpoints: The survey assessed the incidence of acute and delayed nausea and vomiting reported by patients and estimated by their physicians and nurses

As shown in the graph below, a substantial number of patients experience CINV even with conventional antiemetics.

Patients still experience CINV despite treatments

CINV involves a variety of neurotransmitters and receptor systems2,4-9
One reason that CINV is still common is that nausea and vomiting involve a complex signaling process, with many neurotransmitters and receptor systems playing a role.

The complexity of this process is shown in the diagram below. Specifically, chemotherapy impacts three main areas?the GI tract, the chemoreceptor trigger zone (CTZ), and the higher cortical centers. All of these can stimulate the vomiting center and lead to an emetic response.

Antiemetics work at various points in these three pathways. For example, 5-HT3 antagonists act in the GI tract and the brain.

Other agents, such as phenothiazines, block activation of the CTZ.

Cannabinoids are thought to act between higher cortical centers and the medulla?areas where concentrations of cannabinoid receptors are found. Cannabinoids address a different pathway than other conventional antiemetics.

Multiple neurotransmitters and receptor systems are involved in CINV. This means that combinations of antiemetics with different mechanisms are often required for effective therapy.

CINV often leads to other serious consequences
CINV contributes to a reluctance to continue therapy in many patients2,5

In 832 patients, CINV was significantly associated with
Fatigue, anorexia, insomnia10
Deterioration in physical/cognitive functioning10

Conclusions
CINV persists despite treatment in part because chemotherapy causes nausea and vomiting through multiple mechanisms. Combinations of antiemetics, therefore, are often required for effective therapy

(Data and graphics swiped from Marinol)

J-Reel · 04-21-2006, 01:06 PM

madawgz · 04-21-2006, 01:07 PM

awwww cmon, weed is good for your health... fucking bastards

SmokeyTheBear · 04-21-2006, 01:54 PM

it will never happen , they are there to make pharmaceutical companies money period.. pharmaceutical companies dont make anything from something you can grow in your backyard, especially when it replaces some of the most common drugs taken like pain killers

J-Reel · 04-21-2006, 01:56 PM

After Shock Media · 04-21-2006, 01:58 PM

Quote:

Originally Posted by SmokeyTheBear

it will never happen , they are there to make pharmaceutical companies money period.. pharmaceutical companies dont make anything from something you can grow in your backyard, especially when it replaces some of the most common drugs taken like pain killers

Pain killer is not a legit angle, THC makes a very poor pain killer and at most a very mild muscle relaxer when compared to what is available. Where it does shine though is as an anti nausea agent and an appetite stimulant. Neither area that traditional medications have made much headway in effectively.

Choppa · 04-22-2006, 08:36 AM

dang one state in Australia allows it

hydro · 04-22-2006, 08:52 PM

they bought shitty weed.

JD · 04-22-2006, 08:59 PM

the FDA will never fully approve of anything that is natural. If it's something that grows, it's not happening. Fucking pharm corps have their fingers in the FDA in every way shape and form.

I'm all for the use of marijuana for both medical and recreational use. I've never once heard of a stoner stabbing someone for a nickle bag.

King Adam · 04-22-2006, 11:28 PM

Quote:

Originally Posted by SPeRMiNaToR

the FDA will never fully approve of anything that is natural. If it's something that grows, it's not happening. Fucking pharm corps have their fingers in the FDA in every way shape and form.

I'm all for the use of marijuana for both medical and recreational use. I've never once heard of a stoner stabbing someone for a nickle bag.

04-21-2006, 12:27 PM	#1
luv$ !$!$!$!$!$!$!$!$!$!$ Join Date: Dec 2004 Location: Paper Street Posts: 6,158	>> FDA says NO to medical marijuana WASHINGTON (AP) -- The Food and Drug Administration said Thursday that it does not support the use of marijuana for medical purposes. The FDA said in a statement that it and other agencies with the Health and Human Services Department had "concluded that no sound scientific studies supported medical use of marijuana for treatment in the United States, and no animal or human data supported the safety or efficacy of marijuana for general medical use." A number of states have passed legislation allowing marijuana use for medical purposes, but the FDA said, "These measures are inconsistent with efforts to ensure that medications undergo the rigorous scientific scrutiny of the FDA approval process and are proven safe and effective." The statement contradicts a 1999 finding from the Institute of Medicine, part of the National Academy of Sciences, which reported that "marijuana's active components are potentially effective in treating pain, nausea, the anorexia of AIDS wasting and other symptoms, and should be tested rigorously in clinical trials." Bruce Mirken, director of communications for the Marijuana Policy Project, said Thursday: "If anybody needed proof that the FDA has become totally politicized, this is it. This isn't a scientific statement; it's a political statement." Mirken said "a rabid congressional opponent of medical marijuana," Rep. Mark Souder, R-Indiana, asked the FDA to make the statement. Souder, chairman of the House Government Reform subcommittee on drug policy, has said the promotion of medical marijuana "is simply a red herring for the legalization of marijuana for recreational use. Studies have continually rejected the notion that marijuana is suitable for medical use because it adversely impacts concentration and memory, the lungs, motor coordination and the immune system." The FDA statement noted "there is currently sound evidence that smoked marijuana is harmful." It also said, "There are alternative FDA-approved medications in existence for treatment of many of the proposed uses of smoked marijuana." Mirken responded, "There is abundant evidence that marijuana can help cancer patients, multiple sclerosis patients and AIDS patients. There is no scientific doubt that marijuana relieves nausea, vomiting, certain kinds of pain and other symptoms that don't respond well to conventional drugs, and does it more safely than other drugs. "For the FDA to ignore all that evidence is embarrassing," Mirken said. "They should be red-faced." http://www.cnn.com/2006/HEALTH/04/21....ap/index.html __________________ Domain Auction - now till 12:01AM on the 2nd... Paper Streeeeeeeeeeeeeeeeeeeeeeeeeeeeeeet Cash The Real Workout - Innocent High - Oye Loca - Her Freshman Year - Solo Interviews - This Girl Sucks. ** HQ Fresh ORIGINAL sites.

04-21-2006, 12:53 PM	#3
After Shock Media It's coming look busy Join Date: Mar 2001 Location: "Ph'nglui mglw'nafh Cthulhu R'lyeh wgah'nagl fhtagn". Posts: 35,299	It is very typical of them though and I would not expect less. Best part is that the US Government will not allow independant medical labs to have marijuana to do research on the begin with. Then to add in a wonderful twist to the equation. The FDA has approved Marinol a synthetic ingested marijuana. Marinol though has this tricky issue of it being in pill form and thus does nothing for those suffering from nausea since you are prone to throwing it up. Also unlike its natural form a patient can OD on Marinol. So if there are no medical uses for it why then Marinol? As for medical studies. Unintentional weight loss in HIV/AIDS patients is still common, even in this era of highly active antiretroviral therapy (HAART). This unexpected finding has been documented in a cohort of patients from the Tufts University Nutrition for Healthy Living (NFHL) study?a large longitudinal, observational study initiated in February 1995 and continuing through 2005. Patients: Wanke and colleagues1 evaluated 633 HIV/AIDS patients enrolled in the NFHL study. Most of these patients (67%) were on HAART. Participants received nutritional and health assessments at baseline and every 6 months Endpoints: Researchers determined the percentage of patients who met at least one definition of significant weight loss found in the literature As shown in the chart, significant weight loss was common in this population despite the use of HAART. MULTIPLE CLINICAL CHALLENGES IN CANCER Chemotherapy-induced nausea and vomiting (CINV) is still a common problem. Despite treatment with a 5-HT3 antagonist, CINV persists in 40% to 60% of patients on highly emetogenic therapy1 Up to 80% of patients on cisplatin experience delayed CINV2 A recent survey demonstrates that CINV is common even with treatments.3 Participants: The multicenter survey included 298 chemotherapy-naïve patients with cancer and their health care professionals (24 physicians and nurses) Nearly all (97%) of the patients received a 5-HT3 antagonist, 78% received a corticosteroid, and all received either highly (22%) or moderately (78%) emetogenic agents. Endpoints: The survey assessed the incidence of acute and delayed nausea and vomiting reported by patients and estimated by their physicians and nurses As shown in the graph below, a substantial number of patients experience CINV even with conventional antiemetics. Patients still experience CINV despite treatments CINV involves a variety of neurotransmitters and receptor systems2,4-9 One reason that CINV is still common is that nausea and vomiting involve a complex signaling process, with many neurotransmitters and receptor systems playing a role. The complexity of this process is shown in the diagram below. Specifically, chemotherapy impacts three main areas?the GI tract, the chemoreceptor trigger zone (CTZ), and the higher cortical centers. All of these can stimulate the vomiting center and lead to an emetic response. Antiemetics work at various points in these three pathways. For example, 5-HT3 antagonists act in the GI tract and the brain. Other agents, such as phenothiazines, block activation of the CTZ. Cannabinoids are thought to act between higher cortical centers and the medulla?areas where concentrations of cannabinoid receptors are found. Cannabinoids address a different pathway than other conventional antiemetics. Multiple neurotransmitters and receptor systems are involved in CINV. This means that combinations of antiemetics with different mechanisms are often required for effective therapy. CINV often leads to other serious consequences CINV contributes to a reluctance to continue therapy in many patients2,5 In 832 patients, CINV was significantly associated with Fatigue, anorexia, insomnia10 Deterioration in physical/cognitive functioning10 Conclusions CINV persists despite treatment in part because chemotherapy causes nausea and vomiting through multiple mechanisms. Combinations of antiemetics, therefore, are often required for effective therapy (Data and graphics swiped from Marinol) __________________ [email protected] ICQ:135982156 AIM: Aftershockmed1a MSN: [email protected]

04-21-2006, 01:06 PM	#4
J-Reel Confirmed User Join Date: Feb 2002 Location: Boneprone's guest house Posts: 3,782	__________________ Scheck out the new girls at www.hawtmoney.com ICQ 177-447-671

04-21-2006, 01:07 PM	#5
madawgz 8.8.8.8 Industry Role: Join Date: Mar 2006 Location: Noordermarkt Posts: 30,509	awwww cmon, weed is good for your health... fucking bastards __________________ TAEMDLRMSKRJIXMRLSMRJ.

04-21-2006, 01:54 PM	#6
SmokeyTheBear ►SouthOfHeaven Join Date: Jun 2004 Location: PlanetEarth MyBoardRank: GerbilMaster My-Penis-Size: extralarge MyWeapon: Computer Posts: 28,609	it will never happen , they are there to make pharmaceutical companies money period.. pharmaceutical companies dont make anything from something you can grow in your backyard, especially when it replaces some of the most common drugs taken like pain killers __________________ hatisblack at yahoo.com

04-21-2006, 12:29 PM	#2
Rui web Join Date: Dec 2001 Location: On icq: 85-483-060 Posts: 9,533	of course...how could they approve something the big pharma companys cant make money with and everybody can grow themselfs...tskk tskk

04-21-2006, 01:56 PM	#7
J-Reel Confirmed User Join Date: Feb 2002 Location: Boneprone's guest house Posts: 3,782	__________________ Scheck out the new girls at www.hawtmoney.com ICQ 177-447-671

04-22-2006, 08:36 AM	#9
Choppa Confirmed User Join Date: Mar 2006 Location: Webmasters send sexyads.com your dating traffic and live the webmaster dream!! sexyads.com = $$$$$$$$$$ Sexyads adult personals at their greatest since 1997 Earn $$$$$$ today and become one of the thousands of Sexyads Affiliates Posts: 4,079	dang one state in Australia allows it __________________ SexyAds: 10 years in business and still going strong. Become an affiliate today! Choppas ICQ: 283 090 747 Want to know more? [email protected]

04-22-2006, 08:52 PM	#10
hydro Confirmed User Join Date: Dec 2003 Location: Dirty 3rd Posts: 4,216	they bought shitty weed.

04-22-2006, 08:59 PM	#11
JD Too lazy to set a custom title Industry Role: Join Date: Sep 2003 Posts: 22,651	the FDA will never fully approve of anything that is natural. If it's something that grows, it's not happening. Fucking pharm corps have their fingers in the FDA in every way shape and form. I'm all for the use of marijuana for both medical and recreational use. I've never once heard of a stoner stabbing someone for a nickle bag.