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CAHEK 01-02-2005 07:22 PM

50 cures

LeWeekend 01-02-2005 07:36 PM

Actually, there are a few swedish companies developing a vaccination and antibody-based drugs against HIV; http://www.bioinvent.com is one of them. http://www.medivir.com/OuterFrameEng.asp is another Swedish company.

Below are a few of the HIV Drugs in Clinical Development (taken from Medivir homepage):

Compound Phase Originator Licencee
PolymeraseInhibitor NNRTI
Emivirine III Mitsubishi Triangle/Abbott
Capravirine III Shionogi Pfizer
DPC-083 II Du-Pont
TMC-120 II Tibotech
TMC-125 II Tibotech Johnson&Johnson
DPC-961 I Du-Pont
MIV-150 I Medivir Chiron

Polymerase
Inhibitor NRTI
Emtricitabine III Emory Triangle/Abbott
Amdoxovir/DAPD II Emory Triangle/Abbott
MIV-310 II Medivir
Ach-126443 I Yale Achillion Pharma


ProteaseInhibitor
Fosamprinovir III Vertex GSK
Atazanavir III Novartis BMS
Tipranavir II Pharmacia Corp Boehringer-Ingelheim
TMC-114 II Tibotech
AG-1776 I Japan Energy Agouron/Pfizer

* NRTI ? nucleoside reverse transcriptase inhibitors;the most common nucleoside analogues include AZT,ddl,D4T,ddC and 3TC. NNRTI ? non-nucleoside reverse transcriptase inhibitors,also known as allosteric inhibitors,including drugs such as Viramune, Rescriptior and Sustiva,the market leader.

http://www.tripep.se/eng/ is another swedish company focusing on:
? research and clinical development of alpha-HGA, an HIV-inhibiting drug,
? preclinical research focusing on the development of therapeutic and prophylactic vaccines against HIV and Hepatitis C,

Avaris - http://www.avaris.se - another company working on a new type of Hiv-vaccination with a totally new mechanism. Unfortunaly, they are running out of funds :(

Seems like there are plenty of companies, the questions is how long they have come?

wdsguy 01-02-2005 09:19 PM

Whats the point really? cure one worldwide disease, another will just appear that is way more devastating in a coule decades

broke 01-02-2005 09:28 PM

Quote:

Originally Posted by ironlung
if everyone spreads out then there will be no wild life, i think the world no doubt is getting over crowded

I love when people try to talk about over-crowding...

:1orglaugh

SuckOnThis 01-02-2005 09:35 PM

Quote:

Originally Posted by Johny Traffic
OK I'll bite.

Two very simple things to point out.

1. The US government and pharmaceutical companies are not the only governments and pharmaceutical companies in the world looking for a cure. Get a grip please

2. Supposing Im wrong and no one else in the world is looking for a cure. Then keeping something like this a secret would take 1000's of people from government people to doctors from not talking. Now this is where the theory falls down, for two main reasons. Most doctors are doctors because they want to cure people. If they had cured aids they would tell people. But more importantly. I have never met one American who can keep their mouth shut about anything. Let alone 1000's of Americans all keeping their mouths shut about the biggest medical breakthrough in history. Not gonna happen



Well you are wrong. There has not been a disease cured in over 50 years, and there have not been any major medical breakthroughs since, why is that? With all the technological advances nothing has happened except more ways to treat disease. It is a million times more profitable to treat than cure. The people in the know realize if a major disease such as cancer was cured it would literally destroy the economy. One of two things happen when someone is on the verge of a cure, either the drug companies buy the research rights and can it or they are simply labeled a quack.

xxweekxx 01-02-2005 09:43 PM

damn interesting replies

Centurion 01-02-2005 10:20 PM

Quote:

Originally Posted by Dcat
No, I'm not suggesting for a moment that any of the things you mentioned about are "really good for this planet." All I'm saying is that AIDS may be part of the biological process to keep the Earth's carrying capacity in equilibrium. Nothing more.


What you ARE saying is that "this is nature's way of thinning the herd." And I do not buy that.

Centurion 01-02-2005 10:21 PM

Quote:

Originally Posted by doober
December 13, 2004 -- Researchers at Rutgers University in Piscataway, N.J., have developed a trio of drugs they believe can destroy HIV, the virus that causes AIDS, according to a medical journal report.
The drugs, called DAPYs, mimic the virus by changing shape, which enables them to interfere with the way HIV attacks the immune system.

Tests conducted in conjunction with Johnson & Johnson have shown the drugs to be easily absorbed with minimal side effects.

They also can be taken in one pill, in contrast to the drug cocktails currently taken by many AIDS patients.

A research team led by Rutgers chemist Eddy Arnold prepublished details of the most promising of the three drugs, known as R278474, last month in the electronic edition of the Journal of Medicinal Chemistry.

The research has targeted reverse transcriptase, a submiscroscopic protein composed of two coiled chains of amino acids. It is considered HIV's key protein.

"Reverse transcriptase is very important in the biology of AIDS," said Stephen Smith, the head of the department of infectious diseases at St. Michael's Medical Center in Newark.

"If you can really inhibit reverse transcriptase, you can stop AIDS."

The optimism about R278474 stems from its potential to interfere with an enzyme that the virus needs to copy and insert itself into a human cell.




AP



http://www.nypost.com/news/nationalnews/36375.htm

You do know that there have not been ANY human trials so far in regards to these meds you posted about?

Centurion 01-02-2005 10:23 PM

Quote:

Originally Posted by SuckOnThis
Well you are wrong. There has not been a disease cured in over 50 years, and there have not been any major medical breakthroughs since, why is that? With all the technological advances nothing has happened except more ways to treat disease. It is a million times more profitable to treat than cure. The people in the know realize if a major disease such as cancer was cured it would literally destroy the economy. One of two things happen when someone is on the verge of a cure, either the drug companies buy the research rights and can it or they are simply labeled a quack.

Remember when the pronouncement was made that we had wiped out small pox? Now, they're think EVERYONE should get vaccinated for it in case of terrorist attacks.

SuckOnThis 01-02-2005 10:39 PM

Quote:

Originally Posted by Centurion
Remember when the pronouncement was made that we had wiped out small pox? Now, they're think EVERYONE should get vaccinated for it in case of terrorist attacks.

Yep. Another example of how fear is used to create profit.

kmanrox 01-02-2005 11:48 PM

Quote:

Originally Posted by Johny Traffic
OK I'll bite.

Two very simple things to point out.

1. The US government and pharmaceutical companies are not the only governments and pharmaceutical companies in the world looking for a cure. Get a grip please

2. Supposing Im wrong and no one else in the world is looking for a cure. Then keeping something like this a secret would take 1000's of people from government people to doctors from not talking. Now this is where the theory falls down, for two main reasons. Most doctors are doctors because they want to cure people. If they had cured aids they would tell people. But more importantly. I have never met one American who can keep their mouth shut about anything. Let alone 1000's of Americans all keeping their mouths shut about the biggest medical breakthrough in history. Not gonna happen


very good points, I concur wholeheartedly

xxweekxx 01-08-2005 10:11 AM

o :warning

xxweekxx 01-11-2005 06:31 AM

:disgust :upsidedow


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