To the Tsunami relief effort.  
Being part Asian I felt I should do something.  I know it's but a drop in the bucket considering how much they're going to need to rebuild but I had to do something.  
I realize it's a tax write off (give $50k make $100k) but that's not my motive.  I think everyone should give something.  Whether it be $10 or $100,000...just do something.  We're in this together and we all need to help out! 
http://www.redcross.org/  -  Give whatever you can. It doesn't even have to be money. It can be clothing, food, first aid, anything!