I've only owned a small handful of premium adult domains. Two of which were;
HotLesbians.com - I love lesbians
HotLatinas.com - I love latinas
So, as you can see - No major conflict, as of yet. I suppose this is mainly due to contacting only those of which who own domains that 'come to mind' / 'come to interest'. In niches I myself am comfortable with. For some odd reason, a variety of gay/mature/scat domains do not come to mind, when scratching my brain for prospective acquisitions. However -- If one day, I get a random email, stating they're selling "Oldpussy .com" or "Gayfuck.com", regardless of my feelings/interest in the niche. I will of course pursue such an acquisition.
No such moral dilemma will allow me to bypass a profitable domain investment. Let alone pety "personal" discomfort. I'll learn to live with it. Money is still green.
