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The reason i think the problem would potentially affect celebrex and any new anti-COX 2 inhibitors is because is exactly because of it's mechanism
COX-2 inhibitors like celebrex, and vioxx inhibit a specific enzyme cyclooxygenase but they inhibit a specific form of it, the result is LESS chance of gastrointestinal bleeding, so it's safer for something like arthritis.
Good old fashion aspirin inhibits cyclooxygenase too, but it's not specific, as a result there are bleeding risks, a lot of people get bleeding ulcers and a lot of people do die from it..
HOWEVER this thinning of the blood prevents clots from forming and decreases the rate of heart attacks. It's huge, and millions of people are on aspirin exactly for this fact.
The reason people in these trials had an increased risk of heart attacks is because they weren't getting the blood thinning effect.
Anyway you cut it, I'm fairly sure cox-2 inhibitors in older age groups (those most likely with arthritis) is doomed.
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