"I'll spare you the biochemistry, but basically acetaminophen and alcohol in combination overwhelm the liver's ability to remove toxins from your bloodstream." http://www.straightdope.com/columns/000929.html
Just drink water before bed and maybe eat something. Then in the morning take plain old Aspirin.
FYI, your blood sugar can get screwed up easily with lack of sleep and make you feel just like you have a hangover. I've had that problem before, look what time I'm posting...
You judge me for being different, I laugh because you are all the same!
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