Choker, what are you looking to drop on this? If its >50k then bestbuy is not going to cut it for quality.
If you're not looking to go totally crazy, might i recommend the Sony Grand Wega III 70". It's an LCD rear projection system that's about... half a foot deep. Looks like plasma from the front. Quality wise it's top notch too. Can run 1:1 pixel from a HD source and has DVI inputs for a top-notch dvd player or HTPC.
As far as room design goes, check these out.
http://www.cedia.net/awards/elwinners2002.php
But i strongly suggest you get a pro in to design your room's sound, it really doesnt cost much of anything since they'll sell you their own product, and they'll use things like acoustic sensors to map out what the best sound setup is for the room so you have no dead spots.
/audiophile mode off