I have been across the country several times since I can't fly due to prohibitive cost and trains because they aren't very handicap accessible at all stations. Me and my sister just did Dallas to Vegas then from LA back to Dallas. Only took 24 hours from LA to Dallas split in 2 days. We have also done the Hot Rod Power Tour back in 99 when it did the complete Route 66 in 10 days with American Muscle Cars. My wife and I did Dallas to Orlando thru B'Ham/Atlanta and back down I-10 to Dallas. And Dallas to Chicago in 1 day.
I would definitely suggest a comfortable vehicle to ride in because that IS the fun to see everything. We drove all of these in a Cadillac Deville DHS, Cadillac SRX4 or a 96 Impala SS with 500HP+. Our Cadillac actually got 3mpg more with cruise at 80mph going thru LA, MS, AL, GA & FL. Invest $400 in a Valentine 1 Radar Detector/Locator if you want to go over speed limit it WILL make your trip a little better with less visits by the podunk LEO's you might encounter. Always good to slow down going thru small towns especially if loaded down because the LEO's watch the main roads for drug traffickers because they also use large vehicles that are loaded down and they will stop you to take a peek. If you have any questions just post it up there are a lot of road warriors out there.
Oh its also fun sometimes to video certain places because there is a lot to take in sometimes. Just buy one of the windshield mounts for your HD camera and away you go. I took about 3000+ pictures with my iPhone and Canon iS on our adventure to AEE/AVN Awards/ANME in Vegas/LA. You want to take as m,any pictures as possible especially if moving because you might use one out of every 10 shots you take due to motion and movement.
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