Well, if you know anything about marketing, or can market to affiliates well, you should do just fine. I don't know the exact details of them, but there are numerous solo girl sites which make thousands of sales per month (if not more). But, it is all about getting them out there and branding their name. If you don't know marketing, or don't have a marketing team in place, I would suggest building a large team of affiliates to get them out there for you.
Of course as Shap mentioned the content and presentation are HUGE factors as well.
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