>> FDA says NO to medical marijuana

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  • luv$
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    • Dec 2004
    • 6158

    #1

    >> FDA says NO to medical marijuana

    WASHINGTON (AP) -- The Food and Drug Administration said Thursday that it does not support the use of marijuana for medical purposes.

    The FDA said in a statement that it and other agencies with the Health and Human Services Department had "concluded that no sound scientific studies supported medical use of marijuana for treatment in the United States, and no animal or human data supported the safety or efficacy of marijuana for general medical use."

    A number of states have passed legislation allowing marijuana use for medical purposes, but the FDA said, "These measures are inconsistent with efforts to ensure that medications undergo the rigorous scientific scrutiny of the FDA approval process and are proven safe and effective."

    The statement contradicts a 1999 finding from the Institute of Medicine, part of the National Academy of Sciences, which reported that "marijuana's active components are potentially effective in treating pain, nausea, the anorexia of AIDS wasting and other symptoms, and should be tested rigorously in clinical trials."

    Bruce Mirken, director of communications for the Marijuana Policy Project, said Thursday: "If anybody needed proof that the FDA has become totally politicized, this is it. This isn't a scientific statement; it's a political statement."

    Mirken said "a rabid congressional opponent of medical marijuana," Rep. Mark Souder, R-Indiana, asked the FDA to make the statement.

    Souder, chairman of the House Government Reform subcommittee on drug policy, has said the promotion of medical marijuana "is simply a red herring for the legalization of marijuana for recreational use. Studies have continually rejected the notion that marijuana is suitable for medical use because it adversely impacts concentration and memory, the lungs, motor coordination and the immune system."

    The FDA statement noted "there is currently sound evidence that smoked marijuana is harmful." It also said, "There are alternative FDA-approved medications in existence for treatment of many of the proposed uses of smoked marijuana."

    Mirken responded, "There is abundant evidence that marijuana can help cancer patients, multiple sclerosis patients and AIDS patients. There is no scientific doubt that marijuana relieves nausea, vomiting, certain kinds of pain and other symptoms that don't respond well to conventional drugs, and does it more safely than other drugs.

    "For the FDA to ignore all that evidence is embarrassing," Mirken said. "They should be red-faced."



    http://www.cnn.com/2006/HEALTH/04/21....ap/index.html



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  • Rui
    web
    • Dec 2001
    • 9533

    #2
    of course...how could they approve something the big pharma companys cant make money with and everybody can grow themselfs...tskk tskk

    Comment

    • After Shock Media
      It's coming look busy
      • Mar 2001
      • 35299

      #3
      It is very typical of them though and I would not expect less.

      Best part is that the US Government will not allow independant medical labs to have marijuana to do research on the begin with.

      Then to add in a wonderful twist to the equation. The FDA has approved Marinol a synthetic ingested marijuana. Marinol though has this tricky issue of it being in pill form and thus does nothing for those suffering from nausea since you are prone to throwing it up. Also unlike its natural form a patient can OD on Marinol. So if there are no medical uses for it why then Marinol?



      As for medical studies.

      Unintentional weight loss in HIV/AIDS patients is still common, even in this era of highly active antiretroviral therapy (HAART). This unexpected finding has been documented in a cohort of patients from the Tufts University Nutrition for Healthy Living (NFHL) study?a large longitudinal, observational study initiated in February 1995 and continuing through 2005.

      Patients: Wanke and colleagues1 evaluated 633 HIV/AIDS patients enrolled in the NFHL study. Most of these patients (67%) were on HAART. Participants received nutritional and health assessments at baseline and every 6 months

      Endpoints: Researchers determined the percentage of patients who met at least one definition of significant weight loss found in the literature

      As shown in the chart, significant weight loss was common in this population despite the use of HAART.



      MULTIPLE CLINICAL CHALLENGES IN CANCER
      Chemotherapy-induced nausea and vomiting (CINV) is still a common problem.
      Despite treatment with a 5-HT3 antagonist, CINV persists in 40% to 60% of patients on highly emetogenic therapy1

      Up to 80% of patients on cisplatin experience delayed CINV2

      A recent survey demonstrates that CINV is common even with treatments.3

      Participants: The multicenter survey included 298 chemotherapy-naïve patients with cancer and their health care professionals (24 physicians and nurses)

      Nearly all (97%) of the patients received a 5-HT3 antagonist, 78% received a corticosteroid, and all received either highly (22%) or moderately (78%) emetogenic agents.

      Endpoints: The survey assessed the incidence of acute and delayed nausea and vomiting reported by patients and estimated by their physicians and nurses

      As shown in the graph below, a substantial number of patients experience CINV even with conventional antiemetics.

      Patients still experience CINV despite treatments


      CINV involves a variety of neurotransmitters and receptor systems2,4-9
      One reason that CINV is still common is that nausea and vomiting involve a complex signaling process, with many neurotransmitters and receptor systems playing a role.

      The complexity of this process is shown in the diagram below. Specifically, chemotherapy impacts three main areas?the GI tract, the chemoreceptor trigger zone (CTZ), and the higher cortical centers. All of these can stimulate the vomiting center and lead to an emetic response.



      Antiemetics work at various points in these three pathways. For example, 5-HT3 antagonists act in the GI tract and the brain.

      Other agents, such as phenothiazines, block activation of the CTZ.

      Cannabinoids are thought to act between higher cortical centers and the medulla?areas where concentrations of cannabinoid receptors are found. Cannabinoids address a different pathway than other conventional antiemetics.

      Multiple neurotransmitters and receptor systems are involved in CINV. This means that combinations of antiemetics with different mechanisms are often required for effective therapy.



      CINV often leads to other serious consequences
      CINV contributes to a reluctance to continue therapy in many patients2,5


      In 832 patients, CINV was significantly associated with
      Fatigue, anorexia, insomnia10
      Deterioration in physical/cognitive functioning10

      Conclusions
      CINV persists despite treatment in part because chemotherapy causes nausea and vomiting through multiple mechanisms. Combinations of antiemetics, therefore, are often required for effective therapy


      (Data and graphics swiped from Marinol)

      [email protected] ICQ:135982156 AIM: Aftershockmed1a MSN: [email protected]

      Comment

      • J-Reel
        Confirmed User
        • Feb 2002
        • 3782

        #4

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        • madawgz
          8.8.8.8
          • Mar 2006
          • 30509

          #5
          awwww cmon, weed is good for your health... fucking bastards
          TAEMDLRMSKRJIXMRLSMRJ.

          Comment

          • SmokeyTheBear
            ►SouthOfHeaven
            • Jun 2004
            • 28609

            #6
            it will never happen , they are there to make pharmaceutical companies money period.. pharmaceutical companies dont make anything from something you can grow in your backyard, especially when it replaces some of the most common drugs taken like pain killers
            hatisblack at yahoo.com

            Comment

            • J-Reel
              Confirmed User
              • Feb 2002
              • 3782

              #7

              Scheck out the new girls at www.hawtmoney.com

              ICQ 177-447-671

              Comment

              • After Shock Media
                It's coming look busy
                • Mar 2001
                • 35299

                #8
                Originally posted by SmokeyTheBear
                it will never happen , they are there to make pharmaceutical companies money period.. pharmaceutical companies dont make anything from something you can grow in your backyard, especially when it replaces some of the most common drugs taken like pain killers
                Pain killer is not a legit angle, THC makes a very poor pain killer and at most a very mild muscle relaxer when compared to what is available. Where it does shine though is as an anti nausea agent and an appetite stimulant. Neither area that traditional medications have made much headway in effectively.

                [email protected] ICQ:135982156 AIM: Aftershockmed1a MSN: [email protected]

                Comment

                • Choppa
                  Confirmed User
                  • Mar 2006
                  • 4079

                  #9
                  dang one state in Australia allows it

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                  Comment

                  • hydro
                    Confirmed User
                    • Dec 2003
                    • 4216

                    #10
                    they bought shitty weed.

                    Comment

                    • JD
                      Too lazy to set a custom title
                      • Sep 2003
                      • 22651

                      #11
                      the FDA will never fully approve of anything that is natural. If it's something that grows, it's not happening. Fucking pharm corps have their fingers in the FDA in every way shape and form.

                      I'm all for the use of marijuana for both medical and recreational use. I've never once heard of a stoner stabbing someone for a nickle bag.

                      Comment

                      • King Adam
                        Confirmed User
                        • Jul 2003
                        • 5408

                        #12
                        Originally posted by SPeRMiNaToR
                        the FDA will never fully approve of anything that is natural. If it's something that grows, it's not happening. Fucking pharm corps have their fingers in the FDA in every way shape and form.

                        I'm all for the use of marijuana for both medical and recreational use. I've never once heard of a stoner stabbing someone for a nickle bag.

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