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There's plenty enough true stories of people that have tried nearly any drug and died the first time.
Heat death, heart attack, snorting oxy's, whatever. Drugs are a business to be performed by true gamblers. Death is a possibility if you're the wrong person on the wrong day. Len Bias. Rest in Peace.
On hand two, drugs are a higher high. They push people to mental and physical states unachievable by any other methods. I'm highly suspicious of people that are "high on life". Well, maybe that is a good attitude to have really but it's not in the same ballpark. Hell, it's not even the same game. You can't get there without going here.
Then, even more complicated - if you're Wrong Person Number 2, you end up addicted with a life-long problem. This could be cocaine, oxy's, alcohol, whatever. A life-long struggle against yourself and your demons.
This is an interesting duality. Extreme pleasure vs. possible death and addiction. Everyone's risk assessment is different and so we end up with different approaches to the problem. Some will win. Some will lose. Some are going to sing the blues.
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