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Hi FF,
I haven't moved animals, but i do have a little experience with the animal downers a few people have mentioned.
For one of our hurricanes i evacuated over to the west coast (Naples) and took my 2 dogs with me. I have 2 small minpins weighing 5lbs each. The place i stayed at had also had a dog. I wasnt sure how my dogs were going to act with the barometric pressure of the storm + the strange surroundings + another dog present. So, i called my vet and they suggested the pills. My dogs weren't comotose, but groggy and less playful/energentic.
For the situation i was in, it was perfect. I am thinking for the transportation of your little crew- it might be a good idea as well.
Best of luck.
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