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Now you're sitting there with a cactus cutting in your hand, intending to commit felonious cactophagy, and are about to add aggravated weenie-cide unless I can give you a straight answer on how much of that cactus in your hand you should eat. The "maximum safe dose" of mescaline, according to Ott, is 1000 mg. Assume the worst (best) about your cactus, that it is H&B's 2.375% (dry), the most powerful pachanoi known to science. You would therefore not want to take more than 714 gms (fresh), or about 1 1/2 lbs. The threshold dose is about 150 mg, so you'd need at least 107 gms (nearly 4 oz.) to get any effect in the best (worst) case. If you got the wimpy stuff you will need to eat at least 2.5kg to get the least effect. To get the maximum safe dose from the wimpy stuff you need to eat ~17kg; probably about one-fifth your own body weight.
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