IMHO it all depends on the product rather than the payout.
Mainstream business is a completely different ball game to adult business, for some weird reason they (publishers) arent as money grabbing as we are in adult.
For example, a few years ago we launched a new product in mainstream, we gave publishers $50 for a $75 sale, not many pushed the site.
We offered the same product on another network at $1 per sale and everyone pushed it LOL
Nothing changed, the site design was the same, the product was the same, the marketing was the same, but they opted for $1 per sale instead of $50, not that we minded as a company
Also, dont forget, non-adult doesnt really understand the value in the recurring business model, if that is what you are going to use id re-assess your business plan, they simply cant get their heads around the concept
You might do better, again, IMHO, offering a lower payout initially then raising it as you get more publishers pushing your product.
Regards,
Lee