It completely depends on your cash flow needs and risk tolerance.
Is this $50,000 the only source for income you have? Or do you currently already have a job/revenue?
How much of it can you afford to lose? And what type on return on your investment are you looking for short-term/long-term?
The question you asked is sure to get a lot of different responses, because people will advise you to do what they know best. The expert real estate player will tell you to buy property. The paysite guru will recommend you start a paysite.
None of these responses matter. All that matters is what do you want from the money - an ongoing business? a chance to speculate and hit it rich? or a nice long-term investment?
Answer these questions first, and you'll have a better idea of what to do with the money.
Cheers.
p.s. Based on the lack of info you gave, I would advise you to put it in index mutual funds and not touch it for 25 years.
