If you're getting a bunch of popups and browser hijacks it sounds like you got that new VX2 bug and or CoolWWWSearch. I spent 10 hours last week on my mothers computer trying to get rid of it... it's a bitch.
The best option is to get those software people have been mentioning. HijackThis, Spybot and AdAware. There are spyware forums where you post the logs from HijackThis and the people give you a bunch of things to do over and over, it's a pain in the ass but really the only way you can get rid of it.
Here is one of the forums.