I lived there for over 40 years. Been to Mozambique, Botswana, Lesotho, Transkei, Angola, Zimbabwe, Kenya, Tanzania etc and it is all beautiful. Never took malaria tablets because they don't stop you getting malaria. The best is to use either the spray or roll-on mosquito repellents.
The one to watch for is the Tsetse fly in Botswana because one in a million can pass on sleeping sickness and then your fucked. Malaria they can treat but sleeping sickness is another thing.
A great trip is up to the Okanvango swamps in Botswana and you make camp for the night wherever you stop. You hear the lions and hyenas prowling around your camp at night. If you camp at the edge of the water there you will have the hippo's stomping thru the bush at night
