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LeWeekend · 01-02-2005, 07:36 PM

Actually, there are a few swedish companies developing a vaccination and antibody-based drugs against HIV; http://www.bioinvent.com is one of them. http://www.medivir.com/OuterFrameEng.asp is another Swedish company.

Below are a few of the HIV Drugs in Clinical Development (taken from Medivir homepage):

Compound Phase Originator Licencee
PolymeraseInhibitor NNRTI
Emivirine III Mitsubishi Triangle/Abbott
Capravirine III Shionogi Pfizer
DPC-083 II Du-Pont
TMC-120 II Tibotech
TMC-125 II Tibotech Johnson&Johnson
DPC-961 I Du-Pont
MIV-150 I Medivir Chiron

Polymerase
Inhibitor NRTI
Emtricitabine III Emory Triangle/Abbott
Amdoxovir/DAPD II Emory Triangle/Abbott
MIV-310 II Medivir
Ach-126443 I Yale Achillion Pharma

ProteaseInhibitor
Fosamprinovir III Vertex GSK
Atazanavir III Novartis BMS
Tipranavir II Pharmacia Corp Boehringer-Ingelheim
TMC-114 II Tibotech
AG-1776 I Japan Energy Agouron/Pfizer

* NRTI ? nucleoside reverse transcriptase inhibitors;the most common nucleoside analogues include AZT,ddl,D4T,ddC and 3TC. NNRTI ? non-nucleoside reverse transcriptase inhibitors,also known as allosteric inhibitors,including drugs such as Viramune, Rescriptior and Sustiva,the market leader.

http://www.tripep.se/eng/ is another swedish company focusing on:
? research and clinical development of alpha-HGA, an HIV-inhibiting drug,
? preclinical research focusing on the development of therapeutic and prophylactic vaccines against HIV and Hepatitis C,

Avaris - http://www.avaris.se - another company working on a new type of Hiv-vaccination with a totally new mechanism. Unfortunaly, they are running out of funds

Seems like there are plenty of companies, the questions is how long they have come?

01-02-2005, 07:36 PM
LeWeekend Confirmed User Join Date: Jul 2004 Location: Sweden Posts: 288	Actually, there are a few swedish companies developing a vaccination and antibody-based drugs against HIV; http://www.bioinvent.com is one of them. http://www.medivir.com/OuterFrameEng.asp is another Swedish company. Below are a few of the HIV Drugs in Clinical Development (taken from Medivir homepage): Compound Phase Originator Licencee PolymeraseInhibitor NNRTI Emivirine III Mitsubishi Triangle/Abbott Capravirine III Shionogi Pfizer DPC-083 II Du-Pont TMC-120 II Tibotech TMC-125 II Tibotech Johnson&Johnson DPC-961 I Du-Pont MIV-150 I Medivir Chiron Polymerase Inhibitor NRTI Emtricitabine III Emory Triangle/Abbott Amdoxovir/DAPD II Emory Triangle/Abbott MIV-310 II Medivir Ach-126443 I Yale Achillion Pharma ProteaseInhibitor Fosamprinovir III Vertex GSK Atazanavir III Novartis BMS Tipranavir II Pharmacia Corp Boehringer-Ingelheim TMC-114 II Tibotech AG-1776 I Japan Energy Agouron/Pfizer * NRTI ? nucleoside reverse transcriptase inhibitors;the most common nucleoside analogues include AZT,ddl,D4T,ddC and 3TC. NNRTI ? non-nucleoside reverse transcriptase inhibitors,also known as allosteric inhibitors,including drugs such as Viramune, Rescriptior and Sustiva,the market leader. http://www.tripep.se/eng/ is another swedish company focusing on: ? research and clinical development of alpha-HGA, an HIV-inhibiting drug, ? preclinical research focusing on the development of therapeutic and prophylactic vaccines against HIV and Hepatitis C, Avaris - http://www.avaris.se - another company working on a new type of Hiv-vaccination with a totally new mechanism. Unfortunaly, they are running out of funds Seems like there are plenty of companies, the questions is how long they have come?