Incidents of Halloween candy tampering (razor blades, etc.) have been widely over-reported. It's very rare. The last case I remember was like in 1978.
It would be hard to hand out Anthrax candy without a gas mask and gloves, unless the person handing out the candy wanted to risk their own health as well.
If you want to guarantee the safety of your kids...take them to family and friends houses for trick or treating. Also businesses that hand out candy and any local children's museum or school that is having a Halloween festivel.
I've already bought some candy to hand out to the kids...have to stock up on a lot more though...this neighborhood in Indianapolis gets hundreds of kids thru it.
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