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Smoked Marijuana versus Synthetic THC:
"[T]he last thing that they want is a pill when they are already nauseated or are in the act of throwing up." (Mark G. Kris, M.D.)
"[T]he evidence is perfectly clear that smoking is an outstanding route of administration ... for several reasons. One is that the bioavailability is generally very good by the smoked route, and generally very predictable, whereas bioavailability by the oral route [i.e., pills] is both not good and not predictable in general. ... And secondly and very important and useful is the fact that by the smoking route, the person can self-regulate or titrate the dosage so that dosage issues become less important." (Avram Goldstein, M.D.)
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