Like you talking:
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The statin pharmacophore is modified hydroxyglutaric acid component, which is structurally similar to the endogenous substrate HMG CoA and the mevaldyl CoA transition state intermediate. The statin pharmacophore binds to the same active site as the substrate HMG-CoA and inhibits the HMGR enzyme.
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Like I want to hear:
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Shit fucks up your sugar and gives you diabetes!
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But hey, you have a good sense of humor and patience trying to explain it ,before you gave up.I give you Kudos for that. But anyway just found out my sites are not WP.
