
more gadgets, better access of information & education in developing countries, handheld holographic devices, quantum locked levitation used in transport, apparent economical prominence of china, little hubbub about natural disasters causing global awareness (see japan's tsunami), some national borders rearranged (locally significant).
and personally, i'd love to see solar power take over in most daily things because breathing air is good and if i'll have kids, i'm sure they'd enjoy the heck out of it as well.
oh, and the cure for cancer will still be a myth but current life prolonging measures will be more efficient (see HIV)