We don't accept outside advertising on our website but we do use network advertising to bring in new customers so there is definitely some damage done to our marketing by the ad-blocking programs available and used.

That said, we have to consider why consumers are using ad-blocking programs, learn from that knowledge how to make (or place ads) in alternative so that market penetration, and getting the "message across" will still be effective.

There is no point in complaining about what you cannot control -- adapt your own methods to what has become the new norm.