Originally Posted by barcodes

I can only recommend double checking that you dont have any apps that fight for the hotkeys like, i know icq for example messes wth the nums lock key in another program of mine.

If you have a different keyboard, I would plug another one in and test it, just to make double sure it isnt something strange with the keyboard.

If that doesn't work and you are sick of trying things/waiting fro an answer, save all your actions and custom brushes to your desktop, do a fresh install and reload them in ps.

I googled Photoshop hotkey not working mac, and some other terms and people either had problems with the default mac keyboard if it was non us, some language setting on the mac itself. Sorry I can't be more helpful.

Best of luck.