Originally Posted by dallasnovelty

For the kids who dont know what 'ludes are here is excedrpt from the almighty wikipedia

Methaqualone is a sedative drug that is similar in effect to barbituates, a general CNS depressant. Its use peaked in the 1960s and 1970s as a hypnotic, for the treatment of insomnia, and as a sedative and muscle relaxant. It has also been used illegally as a recreational drug, commonly known as Quaaludes (particularly in the 1970s in North America) or as Mandrax (methaqualone 250 mg combined with diphenhydramine 5 mg). In the 2000s, it is widely used in South Africa, "the largest abuser of Mandrax in the world."[1]

Methaqualone was first synthesised in India in 1951 by Indra Kishore Kacker and Syed Hussain Zaheer,[2][3] and was soon introduced to Japanese and European consumers as a safe barbituate substitute.[citation needed] By 1965 it was the most commonly prescribed sedative in Britain, where it has been sold legally under the names Malsed, Malsedin, and Renoval. In 1965 Methaqualone and an antihistamine combination were sold as the sedative drug Mandrax by Rousell Laboratories. At about the same time (1965) it was starting to become a popular recreational drug named mandies or mandrake. In 1972 it was the sixth best selling sedative on the market in the United States,[4] where it was legally sold by the name of Quaalude, and "luding out" was a popular college pastime.[5]