Well far be it for me to jump in here as I might appear to have a bit of a bias as I own
CCBTools, but I do also run 2 NATS programs
Made in Porn and
DreamGirls Cash.
Really there are many advantages to using both CCBill and NATS. CCBill is reliable and has a certain trust level that comes to working with them. The webmasters know that they are getting their checks on the days that they are supposed to get their checks, you can in fact cascade to Epoch if you choose to and the European webmasters can promote many programs through CCBill while only having the expense of cashing 1 check which I know a lot of them really appreciate and has helped them to build their brand loyalty across the pond. There is a definite ease about setting up a CCBill affiliate program and a lot of help along the way to make sure it succeeds.
Of course as a CCBill client you can then use CCBTools for all of your marketing materials and easily provide everyting from FLV XML Feeds and Page Peel Ads to Gallery Builders and POTD or VOTD plus so many more in demand tools.
That being said there is a decent amount of webmasters that only want NATS programs. They are used to the way the stats work, they like the detail that they get back and there are a lot of tools that until CCBTools launched were really only readily available to a NATS prorgram.
I have always found their support helpful, although maybe their system is not as straightforward for a newB to learn how to use.
What I would do if I were coming into Adult today and starting a new program is I would build my new program on CCBill. I would do this for 2 reasons, speed and simplicity. I would also be able to attract more webmasters and traffic to my program giving me a solid base.
Then once I had my base, I would build out from there adding CCBTools to give the webmasters what they need to make my program really fly and to make it keep up with the big guys and all the tools that they provide.
Finally once all that was happening for me, I would then build out the same program on NATS. I would continue to run the CCBTool/CCBill affiliate program for the webmasters that are in there and that are loyal CCBill webmasters but I would build out the NATS to bring in all of the NATS loyal webmasters. I would do CCBill first as it is not an expense, and I would upgrade to NATS once I could aford to take the time to learn it.
Off hand I know of 2 of my clients that do this really well. You can take a look at what they have done here:
XXXSexCash
Dream-Cash
Hope that helps out a little!