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Playing with heavy weights could cause some damage.
If he sticks to lower weights with a decent amount of reps and working on major muscle groups, he should be fine. If at all possible, have him join a gym. There will be lots of people there who will gladly give him some advice when he needs it.
Most cautionary tales about lifting weights at a young age are actually about serious lifting, not about simply working out. If he trains for exercise rather than buffing up, there's no problem at all.
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