Originally Posted by sharphead

Poppers is the street term for various alkyl nitrites taken for recreational purposes through direct inhalation

Inhaling nitrites relaxes smooth muscles throughout the body, including the sphincter muscles of the anus and the vagina. This causes the blood vessels to dilate (which causes a sudden drop in blood pressure), increases heart rate, and produces a sensation of heat and excitement that usually lasts for a couple of minutes.

Alkyl nitrites are often used as a club drug or to enhance a sexual experience. The head rush, euphoria, uncontrollable laughter or giggling, and other sensations that result from the blood pressure drop are often felt to increase sexual arousal and desire. At the same time, the relaxation of the sphincters of the anus and vagina can make penetration easier. It is widely reported that poppers can enhance and prolong orgasms.

While anecdotal evidence reveals that both men and women can find the experience of using poppers pleasurable, this experience is not universal. Some men report that poppers can cause short-term erectile problems.