The answer is probably entirely dependent on what luxuries of life you consider required for comfortable living. Some people can't live without their air conditioning, and others don't like it when horses shit on the path.
There are jungle areas with their deadly scorpions and crazy birds, desert areas that are crazy dry and there are high mountain villages with cool breezes. There are resort towns that pack full of surfers during the high season and there are little villages where not even one person speaks english.
Personally, I love living in open air homes and huts in tiny villages where there are only foot paths and no cars. I like flushing toilets, but cold water showers don't bother me.
Also, there are differences like the east coast has crystal clear water whereas the west is full of more sediment, so if you like snorkelling and such, stick to the east.
You should figure out a list of the things that you really need in a place, and then you have a better idea of where to start looking
