Comodo is a pain in the ass with all this "such and such is putting a hook into this or that and trying to modify a registry entry" Whatever. Nobody understands all that.
I use LookNStop, and I'm surprised it's not more popular. It's extremely lightweight.
http://www.looknstop.com
http://www.wilderssecurity.com/forumdisplay.php?f=28
Then add these rulesets if you need them
http://www.looknstop.com/En/rules/rules.htm