Well, Adobe has just joined the
Linux Foundation and has announced plans to port Adobe Air to Linux. As for other applications, who knows. But it is a start.
Progress takes time. No one thought that a major PC maker would sell Linux desktops and laptops either - but when enough people requested it on Dell's request blog, Dell started selling them. But I guess those people were just wasting their time, huh?
I find it a bit ironic that so many people who almost certainly host their sites on Linux servers are so negative towards it. If you think Windows is so much better, are you using IIS?