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i use the 24-105 f/4L on a 5D about 90% of the time, this combo with IS is superb in low light at slow shutter speeds and because the lens is not f/2.8 it is light enough to carry around all day for sight-seeing.
some vignetting but on less than full-frame body this should not be a prob.
IMO canon IS works better than nikon VR.
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