Just bought the Wacom Intuos2 tonight. Its fantastic! Takes about an hour to get the motions right when you switch from using a mouse. Lets your hand move around a lot more naturally without those repetitive motions and you don't get those wrist pains anymore.
http://www.wacom.com/productinfo/intuos.cfm
It gives you so much precision in Photoshop too which is the main reason I bought it.