I'm actually posting from vista right now... it definitely isn't quite as smooth as I'd like, seems to be programming things. Not performance things.
Anyway, have a look:

The 3D task switcher is cool, but you have to click a button in the quick launch to get it. It would be better if I could map the Alt-Tab to it to use it by default.

Image preview is now more versatile with colour correction, brightness, cropping, resizing and others. Also, you get more info and can set descriptions for them.

The task bar is way more helpful now, by showing thumbnails of what you're working on, and the stacking of similar programs works better too.

The menus are quite different, especially the start menu. But my favorite little handy option is the "Add to QuickLaunch" menu item. That is handy at first.

Explorer is way more intuitive as well... with icons that can go as big or as small as you like... or 'details' view as always. The folder icons actually pan out to show you actual pics, vids, html or what have you coming out. It'll actually show you the first frame of a video in that folder!!
And the information bar along the bottom is very detailed.

The control panel, while WAY better, is also way more complicated. Things are hard to find now, because they've generalized it so much. And getting to some things can require 4 or 5 clicks to get to. But once you do get it, you get some pretty cool results.
This one is a shot of my system specs.
Anyway, that's it for now... I'll have more for you when I have more time
