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They will all work, but chances are you'll run into random programs that don't work and you'll want to switch back. I bet it has changed by now, but last time I tried XP 64bit edition there wasn't even a 64bit flash player.
All in all it just wasn't as stable as I wanted so I decided to wait awhile. 64bit Linux distros work great, but then again you run into the now 64bit flash player thing unless, like I said, is different now.
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